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EPO — NOS1
Text-mined interactions from Literome
Banerjee et al., Kidney Int 2000
:
We hypothesize that
EPO receptors (EPORs) on endothelial cells ( ECs ) in various sites of vasculature may
mediate the activities of
nitric oxide synthase (NOS) and/or the release of endothelin-1 (ET-1), contributing to blood pressure changes ... We show that upon extended exposure,
EPO induces
NOS activity but does not affect ET-1 release
Santhanam et al., Acta Pharmacol Sin 2006
(Vasospasm, Intracranial) :
In this review, we discuss the
EPO induced activation of endothelial
nitric oxide ( NO ) synthase and its contribution to the prevention of cerebral vasospasm
Aoshiba et al., Crit Care Med 2009
(Disease Models, Animal...) :
Erythropoietin also
reduced inducible
nitric oxide synthase expression, nitric oxide production, peroxynitrite formation, and tissue hypoxia
Mihov et al., Am J Physiol Cell Physiol 2009
:
Erythropoietin activates
nitric oxide synthase in murine erythrocytes
Contaldo et al., Shock 2011
:
Erythropoietin requires endothelial
nitric oxide synthase to counteract TNF-[alpha ] -induced microcirculatory dysfunction in murine striated muscle
Su et al., J Cell Physiol 2012
:
AMP activated protein kinase mediates
erythropoietin induced activation of endothelial
nitric oxide synthase
Oba et al., Int J Urol 2012
(Reperfusion Injury) :
Erythropoietin significantly
stimulated phosphorylation of Akt and endothelial
nitric oxide synthase in the kidneys
Adelibieke et al., Circ J 2013
:
Indoxyl sulfate suppressed
EPO induced survival/proliferation, anti-apoptosis function, phosphorylation of endothelial
nitric oxide synthase , and the expression of thrombospondin-1, an erythroid stimulating factor, in HUVECs
Coldewey et al., Kidney Int 2013
:
In the kidneys of endotoxemic wild-type mice,
EPO enhanced the phosphorylation of Akt, glycogen synthase kinase-3ß, and endothelial
nitric oxide synthase , and inhibited the activation of nuclear factor-?B
López Ongil et al., Exp Nephrol 1996
:
Recombinant human
erythropoietin does not
regulate the expression of endothelin-1 and constitutive
nitric oxide synthase in vascular endothelial cells