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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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IL10 — IRF1

Text-mined interactions from Literome

Coccia et al., J Biol Chem 1999 : No significant differences of IRF-1 mRNA expression were found in established Th1 and Th2 cells ; however, interleukin 12 (IL-12) induced a strong up-regulation of IRF-1 transcripts in Th1 but not in Th2 cells
Van Der Fits et al., J Interferon Cytokine Res 2007 (Genetic Predisposition to Disease...) : However, sequence analysis revealed no correlation between SNPs in the IRF-1 promoter and induction of IFN-gamma or IL-10 expression
Chen et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2010 (Anoxia) : [ Interleukin-10 inhibits the expression of interferon regulatory factor-1 with anoxia-reoxygenation in vitro ] ... to explore the effects of IL-10 on the expression of interferon regulatory factor-1 (IRF-1) after anoxia-reoxygenation in vitro ... IL-10 inhibited the expression of IRF-1 in a dose dependent manner compared with anoxia-reoxygenation group, and the peak of inhibitive effects occurred at the dose of 30 µg/L ... IL-10 can inhibit the expression of interferon regulatory factor-1 with anoxia-reoxygenation in vitro
Li et al., Nature 2012 : Moreover, we show that AP1 and IRF complexes cooperatively promote transcription of the Il10 gene, which is expressed in T ( H ) 17 cells and potently regulated by IL-21