Hollnagel et al., J Biol Chem 1999
:
Besides Id3, also the Id1 and Id2 genes were activated by BMP4 in both ES cells and a range of different cell lines
Zhou et al., Scand J Gastroenterol 2009
(Barrett Esophagus) :
Results from a Western blot assay suggest that BMP4 induces activation of smad1 and promotes protein expression of ID2 and CDX2
Wahdan-Alaswad et al., Cancer Res 2010
(Prostatic Neoplasms) :
Similarly, IGF-I suppressed BMP4 induced transcription of the Id1, Id2 , and Id3 genes that are crucially involved in prostate tumor progression through PI3K dependent and mTORC1/2 dependent mechanisms