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BMP4 — TNFRSF11B

Text-mined interactions from Literome

Wan et al., J Biol Chem 2001 : In this study, we have characterized the transcription mechanism of BMP induced OPG gene expression ... Collectively, our data indicate that Hox sites mediate both OPG promoter construct activity and endogenous OPG gene expression in response to BMP stimulation
Tazoe et al., Arch Oral Biol 2003 : Involvement of p38MAP kinase in bone morphogenetic protein-4 induced osteoprotegerin in mouse bone-marrow derived stromal cells ... This study found that bone morphogenetic protein (BMP)-4 markedly increased the level of soluble OPG in the mouse bone-marrow derived stromal cell line, ST2 ... Pre-treatment of ST2 cells with SB203580 ( a specific inhibitor of p38MAP kinase ) inhibited BMP-4 induced increase in OPG , although PD98059 ( a specific inhibitor of classic MAP kinase cascade ) showed no effect on OPG production ... These results clearly suggest that activation of the p38MAP kinase pathway is necessary for BMP-4 induced OPG induction in ST2 cells
Susperregui et al., J Cell Physiol 2008 : Similarly, PTHrP did not significantly modify the BMP regulated expression of RANKL or OPG , cytokines involved in osteoclastogenesis
Hofbauer et al., Biochem Biophys Res Commun 1998 : Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2 , and cytokines