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HGF — SLC22A3

Text-mined interactions from Literome

Yang et al., J Am Soc Nephrol 2005 (Fibrosis...) : Hence, HGF blocks EMT by antagonizing TGF-beta1 's action via upregulating Smad transcriptional co-repressor SnoN expression
Zhang et al., American journal of physiology. Renal physiology 2006 (Fibrosis...) : The effect of HGF on EMT was inhibited by approximately 50 % in the presence of a COX-2 inhibitor SC-58635 ( 10 microM )
Vergara et al., Cancer Lett 2010 (Neoplasm Metastasis...) : In ovarian cancer EMT is induced by transforming growth factor-beta ( TGF-beta ), epidermal growth factor (EGF), hepatocyte growth factor (HGF) and endothelin-1 (ET-1)
Nagai et al., Mol Cancer Ther 2011 (Carcinoma, Hepatocellular...) : The downregulation of E-cadherin expression in HepG2 and Huh7 HCC cell lines shows that HGF mediates the EMT in HCC
Hung et al., J Agric Food Chem 2011 (Breast Neoplasms...) : Briefly, our result suggests a connection between FASN activity and c-Met protein expression and that osthole is a potential compound for breast cancer therapy by targeting the major pathway of HGF/c-Met induced EMT
Sigurdsson et al., PloS one 2011 : Endothelial induced EMT in D492 was partially blocked by inhibition of HGF signaling
Zhang et al., J Biol Chem 2012 (MAP Kinase Signaling System) : CMTM8 overexpression in HepG2 cells inhibited hepatocyte growth factor induced EMT-like morphological changes and cell motility
Barcellos et al., J Biol Chem 2013 (Neoplasm Metastasis) : Cells lacking ARHGAP21 expression show weaker cell-cell adhesions, increased cell migration, and a diminished ability to undergo hepatocyte growth factor induced epithelial-mesenchymal transition (EMT)
Savagner et al., J Cell Biol 1997 : Interestingly, NBT-II cells transfected with antisense Slug cDNA were able to resist EMT induction by FGF-1 or even HGF/SF