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NOX4 — SLC22A3

Text-mined interactions from Literome

Chang et al., Int J Mol Med 2011 (Peritoneal Fibrosis) : The objective of the present study was to investigate the role of NADPH oxidase dependent formation of reactive oxygen species ( ROS ) in the angiotensin II (Ang II) induced epithelial-mesenchymal transition (EMT) and in the accumulation of extracellular matrix ( ECM ) in rat peritoneal mesothelial cells ( RPMCs ) ... In conclusion, NADPH oxidase dependent formation of ROS mediates Ang II dependent EMT and accumulation of ECM in rat peritoneal mesothelial cells
Sancho et al., PloS one 2012 (Hepatitis C, Chronic...) : NOX4 was not necessary for TGF-ß induced epithelial-mesenchymal transition (EMT) , but was required for TGF-ß induced apoptosis in hepatocytes
Lee et al., American journal of physiology. Renal physiology 2013 (Nephrosclerosis) : ROS and NADPH oxidase 4 (Nox4) expression were increased, and antioxidants such as tiron and N-acetylcysteine inhibited EMT induction