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CRK — PRL
Text-mined interactions from Literome
Gerlo et al., Cell Signal 2005
:
We postulate that cAMP induces
PRL expression via two different signalling pathways : a PKA dependent pathway leading to the phosphorylation of CREB, and a PKA independent pathway
leading to the phosphorylation of
p38
Lee et al., Cancer Res 2005
(MAP Kinase Signaling System) :
16-kDa
PRL effectively
inhibited IL-1beta-inducible
p38 MAPK phosphorylation, resulting in blocking Stat1 serine phosphorylation, its subsequent nuclear translocation and activation of the Stat1 target gene IRF-1