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HSD11B2 — LEP

Text-mined interactions from Literome

Liu et al., Diabetes 2003 (Body Weight...) : To assess the role of 11beta-HSD1 mediated synthesis of active corticosterone in leptin related obesity and diabetes, we examined the peripheral effect of leptin on 11beta-HSD1 activity and gene expression in vivo and in vitro in hepatocytes from ob/ob mice and in liver of streptozotocin (STZ) treated ob/ob mice ... In contrast, leptin did not influence 11beta-HSD1 expression in primary hepatocytes from db/db mice, indicating that leptin regulation of 11beta-HSD1 expression is probably mediated by the functional leptin receptor
Fahlbusch et al., Reproductive biology and endocrinology : RB&E 2012 (Fetal Growth Retardation) : We hypothesized that CRH might attenuate syncytialisation, induce leptin , and reduce 11beta-HSD2 expression in primary villous trophoblasts, which are known features of IUGR