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EGF — MAP2K5

Text-mined interactions from Literome

Diaz-Meco et al., Mol Cell Biol 2001 : Here we demonstrate that the aPKCs interact in an EGF-inducible manner with MEK5 and that this interaction is required and sufficient for the activation of MEK5 in response to EGF
Kato-Stankiewicz et al., Proc Natl Acad Sci U S A 2002 (MAP Kinase Signaling System) : They also inhibited Ras induced Raf-1 activation in human embryonic kidney 293 cells, Raf-1 and mitogen activated protein kinase kinase 1 activities in HT1080 fibrosarcoma cells, and epidermal growth factor induced Raf-1 activation in A549 lung carcinoma cells
Moriguchi et al., Eur J Biochem 1995 : Activation of two isoforms of mitogen activated protein kinase kinase in response to epidermal growth factor and nerve growth factor
Kato et al., Nature 1998 : In contrast to Erk1/2, EGF mediated activation of Bmk1 occurs independently of Ras and requires the MAP-kinase kinase Mek5