Gene interactions and pathways from curated databases and text-mining

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FGF4 — NODAL

Text-mined interactions from Literome

Guzman-Ayala et al., Proc Natl Acad Sci U S A 2004 : Here, we show that Fgf4 expression is induced by the transforming growth factor beta related protein Nodal
Maegawa et al., Development 2006 : These experiments show that FGF dependent organizer function operates through both bozozok RNA accumulation and a pathway consisting of beta-catenin -- > Squint -- > FGF -- > Chordin, in which each component is sufficient for expression of the downstream factors of the pathway, and in which Nodal signaling is required for FGF gene expression and FGF signaling is required for Squint induction of chordin
Willems et al., Differentiation 2008 : Additionally, we revealed that the formation of aVE cells from ES cells requires FGF dependent Activin A/Nodal signaling and the attenuation of Bmp4 signaling