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IL2RG — IL6
Text-mined interactions from Literome
Ginn et al., Hum Mutat 2004
(Genetic Diseases, X-Linked...) :
Atypical phenotypes have also been described, but relatively little is known about the mechanisms by which the underlying mutations impair
gammac dependent
interleukin receptor signalling to produce these disease variants
Panzer et al., Clin Exp Immunol 1993
:
We show in this system that exogenously added IL-1 beta,
IL-6 and TNF-alpha
induces IL-2 receptor (R) up-regulation and IL-2 production, and proliferation by both CD4+ and CD8+ cells