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CD40LG — REL
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Schaffer et al., J Immunol 1999
:
Electrophoretic mobility shift assays showed that
p50/p65/c-Rel and STAT-6 are effectively
induced by
CD40L and IL-4, respectively, and bind to specific DNA motifs within the ECS
Iciek et al., J Immunol 1997
:
In addition to the
NF-kappaB/Rel complexes
induced by
CD40L , two nuclear complexes, each which contain both STAT6 and NF-kappaB/Rel proteins, are induced in splenic B cells by a combination of CD40L and IL-4, and bind to the CD40L/IL-4-responsive region of the germline epsilon promoter