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BDNF — MMP9

Text-mined interactions from Literome

Taishi et al., Am J Physiol Regul Integr Comp Physiol 2001 (Sleep Deprivation) : mRNA expression of four molecules [brain derived neurotrophic factor ( BDNF ), activity regulated cytoskeleton associated protein ( Arc ), matrix metalloproteinase-9 (MMP-9) , and tissue plasminogen activator (tPA) ] was determined after 8 h of sleep deprivation and after 6 h of a mild increase in ambient temperature, a condition that enhances sleep in rats
Sartor et al., Clin Exp Metastasis 2002 (Brain Neoplasms...) : At the membrane level, gelatinase MMP-2 -- mainly the activated form -- was restrained by CNTF and BDNF to a residual 34 % with both factors ; membrane-type 1 MMP was down-regulated to 50 % ( 10 h ) and 34 % ( 24 h ) with both factors ; and urokinase-type plasminogen activator was restrained mainly by BDNF to 70 %
Sun et al., Chin Med J (Engl) 2006 : The stimulation of serum starved HUVECs with BDNF caused obvious increase in MMP-2 and MMP-9 mRNA expression and induced the pro-MMP-2 and pro-MMP-9 activation without significant differences in proliferation
Dagnell et al., Translational research : the journal of laboratory and clinical medicine 2007 : Therefore, we studied the effect of NGF, BDNF , and NT-3 on human bronchial smooth muscle cell ( HBSMC ) migration and MMP-2 and MMP-9 secretion ... BDNF , NT-3, and NGF increased MMP-9 , but not MMP-2, secretion as shown by zymography
Zhang et al., Zhonghua Xue Ye Xue Za Zhi 2008 (Multiple Myeloma) : The BDNF induced activation of MMP-9 was inhibited by pretreatment with pyrrolidine dithiocarbamate ( PDTC ), a NF-kappaB inhibitor, or K252 alpha, a specific tyrosine inhibitor of TrkB which is the receptor for BDNF
Kuzniewska et al., Mol Cell Biol 2013 : The BDNF induced MMP-9 transcription was dependent on extracellular signal regulated kinase 1/2 ( ERK1/2 ) pathway and c-Fos expression ... Overexpression of AP-1 dimers in neurons led to MMP-9 promoter activation, with the most potent being those that contained c-Fos, whereas knockdown of endogenous c-Fos by small hairpin RNA ( shRNA ) reduced BDNF mediated MMP-9 transcription ... BDNF stimulation of neurons induced binding of endogenous c-Fos to the proximal MMP-9 promoter region