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PABPC1 — XRN2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 111 proteins (association, tandem affinity purification) Pichlmair et al., Nature 2012

Text-mined interactions from Literome

Bollig et al., Biochem Biophys Res Commun 2003 : The selective interaction with an ARE containing RNA and the phosphorylation by MK2 suggest that PABP1 plays a regulatory role in ARE dependent mRNA decay and its modulation by the p38 MAP kinase cascade
Behm-Ansmant et al., EMBO J 2007 : A conserved role for cytoplasmic poly(A) binding protein 1 ( PABPC1 ) in nonsense mediated mRNA decay
Simón et al., Nucleic Acids Res 2007 : Overall, our results demonstrate a direct involvement of Pab1 in mRNA decay and reveal the modular nature of this factor, with different domains affecting various cellular processes
Meaux et al., Mol Cell 2008 : Nonsense mediated mRNA decay in yeast does not require PAB1 or a poly ( A ) tail