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KCNQ1 — PRKAR1A
Text-mined interactions from Literome
Nicolas et al., Cardiovasc Res 2008
:
We propose that the KCNQ1-KCNE1 channel directly interacts with microtubules and that this interaction plays a major role in coupling
PKA dependent phosphorylation of
KCNQ1 with I ( Ks ) activation
Li et al., J Biol Chem 2012
(Long QT Syndrome) :
Human mutations that disrupt I ( Ks ) -Yotiao interaction result in reduced
PKA dependent phosphorylation of the I ( Ks ) subunit
KCNQ1 and inhibition of sympathetic stimulation of I ( Ks ), which can give rise to long-QT syndrome