Gene interactions and pathways from curated databases and text-mining

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ITGA2 — SYK

Text-mined interactions from Literome

Asazuma et al., Thromb Haemost 1996 : GPIa/IIa plays a key role in p72syk activation induced by collagen, but other collagen receptors may work in synergy to fully activate p72syk
Keely et al., J Biol Chem 1996 : Cross linking of the alpha2beta1 integrin with stimulatory monoclonal antibody against either the beta1 or alpha2 subunit stimulated the phosphorylation of both Syk and PLCgamma2
Melford et al., J Biol Chem 1997 : In the present study we sought to test directly the role of the ITAM/Syk interaction and the role of the Src related kinases in collagen receptor signaling using mouse megakaryocytes