Gene interactions and pathways from curated databases and text-mining

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IL8 — TAT

Text-mined interactions from Literome

Kutsch et al., J Virol 2000 (HIV Infections) : Herein, we demonstrate that HIV-1 Tat ( 72aa ) is a potent inducer of MCP-1, interleukin-8 (IL-8), and IP-10 expression in astrocytes ... Herein, we demonstrate that HIV-1 Tat ( 72aa ) is a potent inducer of MCP-1, interleukin-8 (IL-8) , and IP-10 expression in astrocytes
Hidalgo-Estévez et al., J Gen Virol 2006 : Constitutive or transient Tat expression in Jurkat T cells enhanced cooperative NFAT/AP-1- but not AP-1 dependent transcription independent of its ability to transactivate the HIV-1 LTR
Ott et al., J Immunol 1998 : The HIV-1 transactivator protein Tat increased IL-8 secretion in T cell lines following CD3- and CD28 mediated costimulation ... Full-length Tat ( Tat101 ) enhanced IL-8 transcription through up-regulated transcription factor binding to the CD28-responsive element (CD28RE) in the IL-8 promoter
Poggi et al., J Biol Chem 1998 : Here we demonstrate that Tat inhibits apoptotic body engulfment and interleukin-12 production by blocking extracellular calcium influx