Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Kapasi et al., Nephron. Experimental nephrology 2006 : Interestingly, gp120 at a low dose not only induced NF-kappaB activation but also increased p21 ( cip1/waf1 ) andp27 ( kip1 ) protein levels
Bren et al., PloS one 2009 : Gp120 induced caspase 8 dependent NF-kappaB activation is a novel pathway of HIV replication which increases understanding of the biology of T-cell death, as well as having implications for understanding treatment and prevention of HIV infection
Bruno et al., Gut 2010 (HIV Infections...) : gp120 also induced activation of nuclear factor-kappaB (NF-kappaB) and p38 ( MAPK )
Spadaro et al., PloS one 2013 : Finally, PI-PLC inhibition neither blocks gp120 mediated NF-kB activation nor overall accumulation of CCL2 mRNA, whereas it decreases CCL2 transcript level in the cytoplasm
Jabado et al., Eur J Immunol 1994 : Interaction of HIV gp120 and anti-CD4 antibodies with the CD4 molecule on human CD4+ T cells inhibits the binding activity of NF-AT, NF-kappa B and AP-1, three nuclear factors regulating interleukin-2 gene enhancer activity