Gene interactions and pathways from curated databases and text-mining

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BCR — CDK4

Text-mined interactions from Literome

Tanguay et al., J Immunol 1999 : These results suggest that assembly or stabilization of D-type cyclin holoenzyme complexes 1 ) is an important step in the activation of Cdk4/6 by BCR signals, and 2 ) suffice in providing a mechanism to account for inhibition of BCR stimulated Rb protein phosphorylation by Fc gamma R
Cortez et al., Oncogene 1997 : Here we show that Bcr-Abl signaling prevents down-regulation of cyclin dependent kinase activity and cell cycle arrest after growth factor deprivation of hematopoietic progenitor cells