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CASP3 — NOS1

Text-mined interactions from Literome

Nakagawa et al., J Cell Biochem 2005 : TNF-alpha induced decrease in the number of wild-type cells was significantly prevented by culture with caspase-3 inhibitor ( 10 ( -8 ) M ), while LPS- or Bay K 8644 induced decrease in cell number was significantly prevented by caspase-3 inhibitor or N omega-nitro-L-arginine methylester ( NAME ) ( 10 ( -5 ) M ), an inhibitor of nitric oxide ( NO ) synthase
Gupta et al., J Am Soc Nephrol 2007 (Acute Kidney Injury...) : Treatment of septic animals with APC reduced blood urea nitrogen, renal pathology, and chemokine expression and dramatically reduced the induction of inducible nitric oxide synthase and caspase-3 activation in the kidney
Chuang et al., Neuropharmacology 2007 (Epilepsy, Temporal Lobe...) : In Sprague-Dawley rats, significant and temporally correlated upregulation of NOS II ( 3-24h ), but not NOS I or II expression, enhanced cytosolic translocation of cytochrome c ( days 1 and 3 ), augmented activated caspase-3 in cytosol ( days 1, 3 and 7 ) and DNA fragmentation ( days 1, 3 and 7 ) was detected bilaterally in the hippocampal CA3 subfield after elicitation of sustained seizure activity by microinjection of kainic acid into the unilateral CA3 subfield
Braun et al., Int J Neurosci 2009 (Disease Models, Animal...) : Inducible nitric oxide synthase mediates hippocampal caspase-3 activation in pneumococcal meningitis
Adamczyk et al., FEBS Lett 2010 : The inhibitor of Ca2+ dependent NOS ( N-nitro-L-arginine, 100 microM ) prevented ASN evoked caspase-3 activation and PARP-1 degradation
Chernigovskaya et al., Biotech Histochem 2011 : Thus, we demonstrated that gene disruption of nNOS prevents activation of Bcl-2, p53 and caspase-9 expression during water deprivation, and that nNOS deficiency did not affect survival of magnocellular neurons of the hypothalamus
D'Agostino et al., Biol Psychiatry 2012 (Alzheimer Disease...) : According with the neuroprotective profile of PEA observed during behavioral studies, experimental molecular and biochemical markers induced by Ab25-35 injection, such as lipid peroxidation, protein nytrosylation, inducible nitric oxide synthase induction , and caspase3 activation, were reduced by PEA treatment
Wang et al., Brain Res Bull 2012 (Hypoxia-Ischemia, Brain) : In the meanwhile, the microbubbles attenuated the production of inducible nitric oxide synthase , nitric oxide and tumor necrosis factor-alpha, as well as the activation of caspase-3 in insulted side of brain in neonatal rats
Zhou et al., Am J Physiol Heart Circ Physiol 2013 : Inhibition of NOS prevented H ( 2 ) O ( 2 ) -induced caspase activation, cell apoptosis, and increases in endothelial [ Ca ( 2+ ) ] ( i ) and Lp
Yang et al., Int Immunopharmacol 2013 : Inhibition of NOS could block the activation of caspase-9 , but had no obvious effect on cell apoptosis
Bai et al., Vet Immunol Immunopathol 2013 : Besides, apoptotic rates increase and caspase-3 activation were suppressed by NOS inhibitor or antioxidant