Gene interactions and pathways from curated databases and text-mining

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FGF2 — SCG2

Text-mined interactions from Literome

Sigmund et al., J Biol Chem 1990 (Adrenal Gland Neoplasms...) : Effect of nerve growth factor and fibroblast growth factor on SCG10 and c-fos expression and neurite outgrowth in protein kinase C-depleted PC12 cells ... The role of protein kinase C ( PKC ) in mediating nerve growth factor (NGF) or basic fibroblast growth factor (bFGF) stimulated SCG10 and c-fos expression as well as neurite outgrowth was studied in PC12 cells ... Activators of PKC such as phorbol 12-myristate 13-acetate ( PMA ) or 1-oleoyl 2-acetyl glycerol mimicked the stimulatory effect of NGF and bFGF on SCG10 mRNA levels ... PKC depletion did not affect NGF- or bFGF stimulated SCG10 mRNA induction and bFGF stimulated c-fos mRNA induction ... The results imply that PKC is not involved in NGF- and bFGF stimulated SCG10 mRNA induction and neurite outgrowth
Stein et al., Dev Biol 1988 (Pheochromocytoma) : NGF, FGF , and, to a lesser extent, phorbol esters induced SCG10 , whereas EGF and dibutyryl cAMP did not