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FGF2 — TNF

Text-mined interactions from Literome

Ko et al., Mol Cell Probes 1999 : We could demonstrate in HUAEC that stimulation with IL-1alpha- and TNF-alpha led to the mRNA expression of basic fibroblast growth factor (bFGF) and vascular endothelial growth factor ( VEGF ) which are crucial in the process of angioneogenesis and atherosclerosis as well as of the granulocyte-colony stimulating factor ( G-CSF ), granulocyte macrophage-colony stimulating factor ( GM-CSF ) and stem cell factor (SCF) which are main growth factors in haematopoiesis
Hoshi et al., J Biol Chem 2000 : NF-kappaB was activated after the stimulation of TRAP, bFGF, and TNF-alpha in electrophoretic mobility shift assay, and E5510 suppressed the NF-kappaB activation induced by TRAP and bFGF but not the activation by TNF-alpha
Solomon et al., Invest Ophthalmol Vis Sci 2000 (Pterygium) : Both IL-1beta and TNF-alpha induced a significant decrease in uPA expression in PBF, whereas bFGF induced a slight increase in both HJF and PBF
Rahimi et al., FEBS J 2005 : Endotoxin ( LPS ), interferon gamma (IFNgamma), tumour-necrosis factor (TNF) and TGF-beta did not induce the S100A8 gene in murine fibroblasts whereas FGF-2 induced mRNA maximally after 12 h
Hamanaka et al., J Biol Chem 1992 : We have previously reported that tumor necrosis factor-alpha (TNF-alpha) enhances expression of interleukin-6, collagenase, plasminogen activator inhibitor-1, and basic fibroblast growth factor genes in human omental microvascular endothelial ( HOME ) cells in culture
Hayashi et al., J Obstet Gynaecol Res 2006 : The production of VEGF, bFGF and TGF-beta respectively was enhanced by both IL-1beta and TNF-alpha
Okamura et al., J Biol Chem 1991 : Metabolic labeling and immunoprecipitation assays of bFGF showed that exposure to TNF-alpha enhanced secretion of bFGF into culture medium and also that TNF-alpha stimulated the production of bFGF molecules with molecular masses of 18, 21, and 22.5 kDa in HOME cells ... Therefore, the biological effects of TNF-alpha on HOME cells may be mediated , at least in part, by TNF-alpha induced bFGF
Crisostomo et al., Am J Physiol Cell Physiol 2008 : TNF-alpha , LPS, and hypoxia significantly increased human MSC VEGF, FGF2 , HGF, and IGF-1 production versus controls
Pacios et al., FASEB J 2012 (Diabetes Mellitus, Experimental...) : TNF inhibition in diabetic animals also reduced apoptosis, increased proliferation of bone lining cells, and increased mRNA levels of FGF-2 , TGFß-1, BMP-2, and BMP-6
Schulz et al., J Neurosci 2012 : Furthermore, astrocytes in culture express high levels of FGF-2 in response to IL-1ß, and IGF-1 in response to TNF-a stimulation
Campbell et al., Biochim Biophys Acta 1994 (Joint Diseases) : Tumor necrosis factor alpha (TNF alpha) reduced, and transforming growth factor-beta ( TGF-beta ) and basic fibroblast growth factor (bFGF) increased , the levels of PAI-1 antigen and mRNA in the culture fluids and cell extracts, respectively
Pusztai et al., Cytokine 1993 (Breast Neoplasms) : The effect of epidermal growth factor (EGF), basic fibroblast growth factor (bFGF) and insulin-like growth factor-1 (IGF-1) on the cytostatic activity of tumour necrosis factor-alpha (TNF-alpha) was studied on the breast cancer cell line, T47D
Candela et al., Mol Cell Biochem 1993 : To examine the possible role of basic fibroblast growth factor (FGF) in regulating the effects of TNF alpha, we tested the effect of FGF on TNF alpha mediated PGE2 production and TNF alpha receptor expression in human fibroblasts ... We also found that FGF significantly enhanced TNF alpha receptor expression
Koolwijk et al., J Cell Biol 1996 (Neovascularization, Pathologic) : bFGF and VEGF165 enhanced of the u-PAR by 72 and 46 %, but TNFalpha itself also increased u-PAR in hMVEC by 30 %
Gardner et al., J Biol Chem 1996 : FGF-2 substantially activated the Raf/MEK/MAPK ( where MEK is mitogen activated protein kinase kinase ) pathway but did not affect TNFalpha activation of JNK
Yoshida et al., Mol Cell Biol 1997 : A c-Jun antisense oligonucleotide significantly inhibited TNF-alpha dependent bFGF production but did not affect the production of IL-8 and VEGF
Qu et al., Int Arch Allergy Immunol 1998 : Immunostaining, RT-PCR, ELISA, immunoblot and Northern blot analyses were employed to study four murine MC lines for FGF-2 expression and its regulation by transforming growth factor-beta ( TGF-beta ), stem cell factor (SCF), and tumor necrosis factor-alpha (TNF-alpha) ... Expression of FGF-2 may be a ubiquitous feature of MC in other species in addition to humans, and can be selectively regulated by SCF, TGF-beta and TNF-alpha
Faris et al., AIDS 1998 (Acquired Immunodeficiency Syndrome...) : OSM, IL-1 and TNF-alpha induced the transcriptional activation of a bFGF promoter reporter gene in parallel with the activation of an AP-1 reporter
Selzman et al., Surgery 1998 : The class II cytokine receptor ligands, IL-10 and IFN, inhibit cytokine- ( TNF ) and growth factor- ( FGF ) induced VSMC proliferation