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IL2RA — TLR2
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Han et al., Infect Immun 2003
:
The target cells used in the study were peripheral blood mononuclear cells ( PBMCs ) and two model cell lines ( CHO/CD14/TLR2 and CHO/CD14/TLR4 ) that express human
CD25 protein in
response to
Toll-like receptor 2 (TLR2) and TLR4 stimulation, respectively
Maxwell et al., J Immunol 2004
:
TLR stimulation
induced an increase in
CD25 expression, acquisition of surface MHC class II, and abnormally high increases in forward and side scatter of the peptide-specific T cells
Farina et al., Int Immunol 2004
:
Both
TLR-ligands and inflammatory cytokines
induced the expression of
CD25 , CD69, CD80 and, surprisingly, also of CD83, commonly regarded as an activation marker for mature dendritic cells ( DC )
Brisslert et al., Immunology 2006
:
CD25 expression on B cells was selectively
up-regulated by Toll-like receptor 2 (TLR2),
TLR4 , and TLR9 ligands but not by a TLR3 ligand or Epstein-Barr virus ( EBV ) stimulation ...
CD25 expression on B cells was selectively
up-regulated by
Toll-like receptor 2 (TLR2) , TLR4, and TLR9 ligands but not by a TLR3 ligand or Epstein-Barr virus ( EBV ) stimulation
Wang et al., Eur J Immunol 2009
(Schistosomiasis japonica) :
CD4+CD25+ Treg induction by an HSP60 derived peptide SJMHE1 from Schistosoma japonicum is
TLR2 dependent ... Furthermore, our data support a
role for
TLR2 in SJMHE1 mediated CD4 ( + )
CD25 ( + ) Treg induction
Piconi et al., AIDS 2010
(HIV Infections) :
Activated T cells ( Ki67 ( + ) ), Treg lymphocytes ( CD4 ( + )
/CD25high/Foxp3+ ), divided into naive and activated cells based on PD1 expression, interleukin (IL)-10 and transforming growth factor ( TGF ) -beta production, annexin V,
activation of caspases 8 and 9,
Toll-like receptor (TLR)2 and TLR4 expression on immune cells, and plasma lipopolysaccharide (LPS) concentration were analyzed