Gene interactions and pathways from curated databases and text-mining

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ADIPOQ — TNF

Text-mined interactions from Literome

Ruan et al., Diabetes 2002 (Insulin Resistance) : A 4-day TNF-alpha infusion caused insulin resistance and significant elevation of plasma levels of FFAs and triglycerides and reduction of ACRP30
Wulster-Radcliffe et al., Biochem Biophys Res Commun 2004 : Adiponectin , an adipocyte derived hormone, attenuates the production of TNFalpha by activated human macrophages ... Adiponectin suppressed both TNFalpha and IL6 production in macrophages activated with lipopolysaccharide ( P < 0.01 )
Saijo et al., Biochem Biophys Res Commun 2005 : Adiponectin , an adipocyte derived hormone, reportedly suppresses the production of TNF-alpha and IL-6 by LPS stimulated human or porcine macrophages, and the phagocytosis of microbeads by human macrophages
Weigert et al., FEBS Lett 2005 : Adiponectin exerts anti-inflammatory effects in LPS treated monocytic cells and CORS-26 also reduces IL-6 and TNF-alpha secretion but does not increase IL-10
Sonoda et al., Endocrinology 2008 : Adiponectin and leptin, and adipocyte-specific genes of adiponectin, leptin, and PPAR-gamma were detected in culture assembly, whereas the lipogenesis factor insulin ( 20 mU/ml ) and inflammation related agent TNF-alpha ( 2 nm ) increased and decreased, respectively, all of their displays
Maia-Fernandes et al., Rev Port Cardiol 2008 (Atherosclerosis...) : Adiponectin secretion is inhibited by TNF-alpha and by catecholamines, and is stimulated by PPAR gamma activation
Zhou et al., Cardiovascular diabetology 2011 (Coronary Artery Disease) : Adiponectin suppressed secretion of IL-6 and TNF-a in stimulated monocytes and TLR4 was expressed on cell surfaces