Gene interactions and pathways from curated databases and text-mining

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IL18 — SOAT1

Text-mined interactions from Literome

Walker et al., Arch Virol Suppl 2005 (Ehrlichiosis) : Ehrlichiae attach to L-selectin and E-selectin, inhibit phagolysosomal fusion, apoptosis, and JAK/STAT activation, and downregulate IL-12, IL-15, IL-18 , TLR2 and 3, and CD14
Wang et al., Blood 2008 (MAP Kinase Signaling System) : IL-12 and IL-18 stimulated autoreactively activated NKT cells to secrete IFN-gamma, and this was mediated by Janus kinase-signal transducers and activators of transcription ( JAK-STAT ) -dependent signaling without induction of calcium flux
Fortin et al., FASEB J 2009 (Inflammation) : By contrast, the phosphorylation and DNA binding activity of various STAT proteins were not induced by IL-18
Seidel et al., Proc Natl Acad Sci U S A 1995 (Carcinoma, Hepatocellular...) : We have systematically examined the effects of the spacing between the TT and AA core half sites on the binding of the STAT complexes activated by IFN-gamma, interleukin (IL) 6, granulocyte-macrophage colony stimulating factor, and IL-4