We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to TNF

NR4A2 — TNF

Text-mined interactions from Literome

McEvoy et al., J Immunol 2002 (Arthritis, Rheumatoid) : We have established that transcriptional activation of the NURR1 gene by IL-1beta and TNF-alpha requires a proximal promoter region that contains a consensus NF-kappaB DNA binding motif
Liu et al., Biochem Biophys Res Commun 2005 : RG and PG attenuated TNFalpha mediated induction of trans acting factor ( s ) Nur77/Nurr1 and binding of nuclear proteins ( NP ) to the cis acting element ( NBRE )
O'Kane et al., J Invest Dermatol 2008 (Psoriasis) : Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition
Aherne et al., Mol Immunol 2009 (Arthritis) : Transcriptional effects of NR4A2 on the human IL-8 promoter are enhanced in the presence of TNF-alpha , suggesting molecular crosstalk between TNF-alpha signalling and NR4A2