UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to PRKAG2

PRKAG2 — STAT3

Pathways - manually collected, often from reviews:

KEGG Adipocytokine signaling pathway: STAT3 → PRKAA1/PRKAA2/PRKAB1/PRKAB2/PRKAG1/PRKAG2/PRKAG3 (protein-protein, inhibition)

Text-mined interactions from Literome

Uotani et al., Biochem Biophys Res Commun 2006 : These findings suggest that the activation of JAK2, but not STAT3 , may play a critical role in leptin induced AMPK activation in Huh7 cells
Kim et al., Diabetologia 2012 (Insulin Resistance) : IL-6 induced STAT3 transactivation and SOCS3 production were significantly repressed by metformin, adenoviral constitutively active AMPK ( Ad-CA-AMPK ), and adenoviral SHP ( Ad-SHP ), but not in Shp knockdown, or with the adenoviral dominant negative form of AMPK ( Ad-DN-AMPK )