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IL10 — PRKAB1

Text-mined interactions from Literome

Giri et al., J Neurosci 2004 (Inflammation) : A pharmacological activator of AMPK , 5-amino-4-imidazole carboxamide riboside ( AICAR ) inhibited lipopolysaccharide (LPS) induced expression of proinflammatory cytokines ( tumor necrosis factor alpha, interleukin-1beta , and interleukin-6 ) and inducible nitric oxide synthase in primary rat astrocytes, microglia, and peritoneal macrophages
Łabuzek et al., Neurotoxicology 2010 : The presented evidence supports the conclusion that AMPK activated by AICAR is involved in regulation of ROS and cytokine production ( IL-1 beta, TNF-alpha ( 6h ), IL-10 and TGF-beta ) as well as arginase I and PGC-1alpha expression
Łabuzek et al., Pharmacol Rep 2010 : Furthermore, the effects of metformin on the release of IL-1ß, IL-6, IL-10 , TGF-ß, NO, and ROS as well as on the expression of arginase I, iNOS, NF-?B p65 and PGC-1a were not AMPK dependent , because pretreatment of LPS activated microglia with compound C, a pharmacological inhibitor of AMPK, did not reverse the effect of metformin