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NFKBIA — SNAP25

Text-mined interactions from Literome

Simpson et al., J Neurochem 1999 : Simultaneously, the cytoplasmic expression of phosphorylated inhibitory protein IkappaB alpha was dramatically increased by SNAP ( 200 microM ), LPS ( 10 microg/ml ), and kainate ( 50 microM ) treatment
Kalra et al., Circulation 2000 : SNAP and 8-Br-cGMP were both sufficient to lead to the site-specific phosphorylation ( serine 32 ) and degradation of IkappaBalpha in isolated cardiac myocytes
Chang et al., Exp Mol Med 2004 : SNAP also blocked cytokine- induced increase in NF-kappaB activation, iNOS promoter activity, nuclear translocation of cytosolic NF-kappaB p65 subunit, and IkappaBalpha degradation, which correlated with its inhibitory effect on phosphorylation and ubiquitination of IkappaB