Gene interactions and pathways from curated databases and text-mining

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EEF1A2 — IL6

Text-mined interactions from Literome

Bessler et al., Clin Immunol 2005 : The in vitro effect of the hydrophilic statin - pravastatin - and three hydrophobic statins - atorvastatin, lovastatin and simvastatin - on the production of IL-1beta, IL-1ra, IL-2, IL-6 and IFN-gamma by human peripheral blood mononuclear cells ( PBMC ) and their response to mitogens was examined
Zhang et al., J Immunol 2008 (Multiple Sclerosis) : Our results demonstrated statin mediated increases in suppressor of cytokine secretion (SOCS) 3 and suppressor of cytokine secretion 7, which negatively regulate the STAT/JAK signal transduction pathway and IL-6 and IL-23 gene expression in monocytes