Gene interactions and pathways from curated databases and text-mining

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PCNA — TAT

Text-mined interactions from Literome

Chun et al., Cancer Lett 2004 : PEP8-TAT2 , a membrane-permeable peptide, inhibits cyclin-Cdk2 activity in HeLa cells
Ramakrishnan et al., J Cell Physiol 2012 (Calcium Signaling) : In reporter plasmid assays, inhibition of the Ca ( 2+ ) signaling pathway repressed the PCNA promoter and HIV-1 Tat transactivation of the HIV-1 LTR, but not HTLV-1 Tax transactivation of the HTLV-1 LTR, suggesting that perturbation of the Ca ( 2+ ) pathway and reduction of Cdk9 T-loop phosphorylation inhibits transcription units that have a rigorous requirement for P-TEFb function