Syljuåsen et al., Mol Cell Biol 2005
:
Chk1-inhibition triggered rapid, pan-nuclear phosphorylation of histone H2AX, p53, Smc1 , replication protein A, and Chk1 itself in human S-phase cells
Horton et al., DNA repair 2011
:
NBS1 expression had little effect on ATR mediated phosphorylation of Chk1 and ATM mediated phosphorylation of Chk2 in response to MMS+4-AN. Phosphorylation of SMC1 was also observed in response to MMS+4-AN treatment