Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MRAS

Text-mined interactions from Literome

Guo et al., Oncogene 2005 (Leukemia, Mast-Cell...) : Inhibition of either Erk or PI3 kinase blocked the capacity of both activated M-Ras and activated H-Ras to support proliferation and viability
Saito et al., EMBO Rep 2009 : M-Ras ( Q71L ) stimulated extracellular signal regulated kinase ( ERK ) activation, inducing dendrite growth, whereas Sema4D suppressed ERK activity and down-regulation of ERK was required for a Sema4D induced reduction of dendrite growth