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ARG1 — NFKB1
Text-mined interactions from Literome
Klasen et al., Br J Pharmacol 2001
:
5. Two different inhibitors of the
NF-kappa B-pathway also
prevented LPS induced increase in
arginase activity
Rakonczay et al., Free Radic Biol Med 2003
(Acute Disease...) :
We demonstrated that
Arg specifically and dose-dependently induces pancreatitis,
activates NF-kappaB ( only the 3 g/kg dose ) and proinflammatory cytokine synthesis, and increases the expressions of HSP60 and HSP72 in the pancreas of rats
Yang et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2003
:
L-Arg augmented CSE induced
NF-kappaB activation and decreased I-kappaB content at low concentration while inhibited CSE induced NF-kappaB activation at high concentration, but there was not any significant difference of the expression of I-kappaB
Moreau et al., Mol Pharmacol 2007
:
Lys-des-Arg9-bradykinin had little effect on
NF-kappaB activation, the Bmax, or receptor mRNA abundance or stability
Ckless et al., Am J Respir Cell Mol Biol 2007
:
Our results demonstrate that reduction of
arginase activity enhanced cellular content of NO and S-nitrosated proteins, and
resulted in decreases in TNF-alpha- or LPS stimulated
NF-kappaB DNA binding and transcriptional activity, in association with enhanced S-nitrosation of p50 ... Conversely, overexpression of
arginase I decreased cellular S-nitrosothiol content and
enhanced IkappaB kinase activity and
NF-kappaB DNA binding, and decreased S-nitrosation of p50