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ECI1 — NFKB1
Text-mined interactions from Literome
Hecker et al., FEBS Lett 1996
:
DCI , but not NAS, also
suppressed the activation of
NF-kappa B in VSMC exposed to IL-1 beta, while no significant NF-kappa B activation was detected in forskolin treated cells
Hecker et al., Br J Pharmacol 1996
:
The inhibitory
effect of
DCI on
NF-kappa B activation, however, does not seem to be related to its antioxidative properties, since DCI, unlike chrysin or NAS, is a potent serine protease inhibitor which stabilizes the inactive NF-kappa B complex by protecting the inhibitory I kappa B-alpha subunit from proteolytic degradation