Zack et al., Atherosclerosis 2011
(Aortic Aneurysm, Abdominal...) :
Ang II induction of cyclooxygenase-2, interleukin-6 , matrix metalloproteinase (MMP)-2, MMP-13 and MMP-14 was reduced significantly in GX DKO mice compared to apoE ( -/- ) mice
Valente et al., J Mol Cell Cardiol 2012
(Cardiomegaly...) :
Further, Ang-II induced IKK/p65 and JNK/c-Jun phosphorylation, NF-?B and AP-1 activation, and IL-18 and MMP-9 expression were also markedly attenuated in CIKS-null mice