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PLAU — SERPINB5

Text-mined interactions from Literome

McGowen et al., Cancer Res 2000 (Prostatic Neoplasms) : The goal of this study was to investigate the effect of maspin on cell surface associated uPA ... Purified recombinant maspin produced in baculovirus infected Spodoptera frugiperda Sf9 insect cells [ rMaspin ( i ) ] binds specifically to the surface of DU145 cells, inhibits the DU145 cell surface bound uPA , and forms a stable complex with the uPA in DU145 cell lysate
Biliran et al., Cancer Res 2001 (Prostatic Neoplasms) : In addition, maspin expression led to a dramatic reduction in the release of active uPA , both high molecular weight and the low molecular weight, into the conditioned culture medium ... The inhibitory effect of maspin on pericellular uPA correlates with significantly decreased cell invasion potential and motility in vitro
Cher et al., Proc Natl Acad Sci U S A 2003 (Bone Neoplasms...) : Previously, we showed that maspin , a serine protease inhibitor, specifically inhibits PC-associated uPA and PC cell invasion and motility in vitro
Schaefer et al., Cancer Biol Ther 2005 (Breast Neoplasms) : Hypoxia effects : implications for maspin regulation of the uPA/uPAR complex
Yin et al., Cancer Res 2006 (Prostatic Neoplasms) : The maspin effects on surface associated uPA and uPAR required the interaction between uPA and uPAR
Endsley et al., J Biol Chem 2011 : In addition, we demonstrate that the urokinase-type plasminogen activator ( uPA ) /uPA receptor (uPAR) complex is required for the localization and adhesion function of maspin
Warejcka et al., Exp Eye Res 2011 : This study suggests that extracellular maspin increased pro and active uPA and tPA released by corneal fibroblasts and myofibroblasts on the short time scale of 1-4 h, but by 24 h there was no increase over the levels produced without maspin ... It further indicates that the effect of maspin on uPA and tPA levels is cell type dependent