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PLAU — TNFSF10

Text-mined interactions from Literome

Zhou et al., Hepatobiliary Pancreat Dis Int 2008 (Pancreatic Neoplasms) : The purpose of this study was to find out if TRAIL could induce the expression of uPA , IL-8, MMP-7 and MMP-9.and to explore the corresponding potential signaling transduction pathway in pancreatic cancer cells ... TRAIL can stimulate the expression of uPA , IL-8, MMP-7 and MMP-9 in pancreatic cancer cell lines, especially in Colo357wt ... The members of caspases, MEK1/2, PKC, and NF-kappaB are involved in TRAIL induced expression of uPA , IL-8, MMP-7 and MMP-9
Zhou et al., Hepatobiliary Pancreat Dis Int 2013 (Adenocarcinoma...) : TRAIL induced expression of uPA and IL-8 strongly enhanced by overexpression of TRAF2 and Bcl-xL in pancreatic ductal adenocarcinoma cells ... Overexpression of TRAF2 or Bcl-xL strongly increased TRAIL mediated upregulation of uPA and IL-8 ... In PDAC cells, TRAIL strongly induced uPA and IL-8 via TRAIL-R1