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BAX — TFAP2A

Text-mined interactions from Literome

Wang et al., Mol Cell Biochem 2009 (HIV Infections) : c-FLIPL expression reduced AP-2 protein levels required to promote PKC protein expression and PKC associated inactive form of Bax, and inhibited Bax activation, suggesting that c-FLIPL inhibits Bax activation via modulating PKC expression at the transcriptional level involving AP-2 during gp120 treatment
Zhang et al., J Mol Histol 2012 : AP-2a dependent regulation of Bcl-2/Bax expression affects apoptosis in the trophoblast ... However, it is not clear whether AP-2a affects apoptosis in trophoblast cells and whether it regulates expression of apoptosis related factors Bcl-2 and Bax ... Furthermore, overexpression of AP-2a increased Bax expression and decreased Bcl-2 expression, whereas down-regulation of AP-2a expression resulted in a decrease in Bax expression and an increase in Bcl-2 expression ... AP-2a regulates expression of Bcl-2 and Bax and apoptosis in BeWo cells ... These results suggest that AP-2a mediated regulation of Bcl-2 and Bax regulation influences apoptosis which in turn leads to the pathogenesis of preeclampsia