Gene interactions and pathways from curated databases and text-mining

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BDNF — HRAS

Text-mined interactions from Literome

Chaïb-Oukadour et al., J Neurochem 2004 : Hc-TeTx also induces phosphorylation of the tyrosine kinase BDNF receptor, activation of p21Ras in its GTP bound form, and phosphorylation of the cascade including extracellular-signal regulated kinases-1/2 ( ERK-1/2 ), p90 ribosomal S6 kinase (p90rsk) and CREB ( cAMP-response-element binding protein )
Carter et al., J Biol Chem 1995 : Differential regulation of p21ras activation in neurons by nerve growth factor and brain derived neurotrophic factor
Zirrgiebel et al., Neurochem Res 1996 : Thus, p21 Ras and PLC gamma were activated by BDNF but not by NT-3 whereas both BDNF and NT-3 increased calcium and c-fos mRNA in the granule neurons