◀ Back to EPHB2
E2F5 — EPHB2
Text-mined interactions from Literome
Grewal et al., J Biol Chem 2001
:
This transactivation resulted in the initiation of multiple cellular signals ( phosphorylation of the EGFRs and
ERK and
activation of cAMP-responsive element binding protein ( CREB ), NF-kappaB, and
E2F ), as well as subsequent rapid down-regulation of cell-surface EGFRs and internalization and desensitization of the EGFRs without change in the total cellular complement of EGFRs
Fang et al., Cell Immunol 2009
:
ERK1/2 activation
leads to the release of
E2F that could bind to the E2F binding sites in the inverted CCAAT box binding protein ( ICBP90 ) gene promoter
Paquin et al., BMC cell biology 2013
(Adenoma...) :
Treatment of quiescent HIEC with serum
induced ERK1/2 activation, E2F4 phosphorylation,
E2F4 nuclear translocation and G1/S phase transition while inhibition of
MEK/ERK signaling by U0126 prevented these events