Gene interactions and pathways from curated databases and text-mining

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EPHB2 — NPEPPS

Text-mined interactions from Literome

Gioeli et al., Mol Endocrinol 2006 (Prostatic Neoplasms) : Stress kinase inhibition of PSA transcription is, therefore, dependent on the AR. Similar experiments involving either activation or inhibition of MAPK/ERK kinase : ERK signaling had little effect on Ser 650 phosphorylation or PSA mRNA levels
Shigemura et al., Prostate 2009 (MAP Kinase Signaling System...) : We observed ERK kinase inhibitor, U0126, but not phosphatidylinositol 3-kinase (PI-3K), LY294002, or protein kinase A (PKA) inhibitor, H-89, inhibited stromal CM or androgen induced PSA promoter luciferase activities, and anchorage independent growth of LNCaP cells