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EPHB2 — TRPC6

Text-mined interactions from Literome

Zhang et al., Experimental biology and medicine (Maywood, N.J.) 2009 : TRPC6 up-regulation in Ang II-induced podocyte apoptosis might result from ERK activation and NF-kappaB translocation
Li et al., Am J Respir Cell Mol Biol 2013 (Calcium Signaling...) : Real-time quantitative PCR was used for the measurement of mRNA, Western blotting was used for the measurement of protein, and fluorescent microscopic for [ Ca ( 2+ ) ] i was used to determine the involvement of p38 and extracellular regulated kinase (ERK)-1/2 mitogen activated protein kinase ( MAPK ) signaling in BMP4 induced TRPC expression and the elevation of [ Ca ( 2+ ) ] i in PASMCs
Chiluiza et al., J Biol Chem 2013 (Glomerulosclerosis, Focal Segmental) : In 293T cells and cultured podocytes, overexpression of gain-of-function TRPC6 mutants resulted in increased ERK1/2 phosphorylation, an effect dependent upon channel function ... Phosphorylation of Thr-70, Ser-282, and Tyr-31/285 were not necessary for ERK activation by mutant TRPC6 , although a phosphomimetic TRPC6 S282E mutant was capable of ERK activation