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NOS3 — RAC1

Text-mined interactions from Literome

Gonzalez et al., J Biol Chem 2006 : Taken together, these studies identify G protein betagamma subunits, Src kinase and the GEF Tiam1 as upstream modulators of S1P mediated Rac1 activation, and establish a central role for Rac1 in S1P mediated activation of PI 3-kinase/Akt/endothelial nitric-oxide synthase signaling in vascular endothelial cells
Sawada et al., Circ Res 2008 (Disease Models, Animal...) : Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1 ... Indeed, Rac1 promotes eNOS gene transcription through p21 activated kinase but not NADPH oxidase, increases eNOS mRNA stability, and enhances eNOS activity by promoting endothelial uptake of l-arginine
Ramseyer et al., Hypertension 2012 : Myosin light chain kinase, NO, protein kinase C, mitogen activated kinase kinase, c-Jun amino terminal kinases, and Rac-1 were also not involved in TNF-a induced decreases in NOS3 expression