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RELA — THOC1
Text-mined interactions from Literome
Doostzadeh-Cizeron et al., J Biol Chem 2000
:
Expression of
p84N5 also
leads to activation of
NF-kappaB as indicated by nuclear translocation of p65RelA and transcriptional activation of a NF-kappaB dependent reporter promoter
Guo et al., PloS one 2012
(Breast Neoplasms...) :
We subsequently identify several transcriptional factors, including NF-?B binding sites in the hTREX84 gene promoter and demonstrate by chromatin immunoprecipation ( ChIP ) and site directed mutagenesis that
RelA/p65 binds the NF-kB binding sites and
induces hTREX84 expression ... Our results indicate that overexpression of
hTREX84 is associated with cancer cell transformation, proliferation and may be
regulated by
RelA/p65