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IGF2 — PXN

Text-mined interactions from Literome

Mañes et al., Mol Cell Biol 1999 (Neoplasm Invasiveness) : On the other hand, IGF-I promotes the association of insulin receptor substrate 1 with the focal adhesion kinase ( FAK ), paxillin , and the tyrosine phosphatase SHP-2, resulting in FAK and paxillin dephosphorylation
Tai et al., Cancer Res 2003 (Multiple Myeloma) : In addition, IGF-I triggers polymerization of F-actin, induces phosphorylation of p125(FAK) and paxillin , and enhances beta1 integrin interaction with these focal adhesion proteins
Genua et al., PloS one 2012 (Carcinoma...) : FAK and its homolog Proline-rich tyrosine kinase 2 (Pyk2) modulate paxillin activation ; however, their role in regulating IGF-IR dependent signaling and motility in bladder cancer has not been established