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González-Rodriguez et al., J Cell Physiol 2007
:
In serum deprived PTP1B(+/+PTP1B) hepatocytes, a rapid entry of Foxo1 into the nucleus and an earlier activation of caspase-8 was observed
Siqueira et al., Diabetologia 2010
(Diabetes Mellitus, Experimental...) :
Diabetic wounds had increased TNF-alpha, fibroblast apoptosis, caspase-3/7 activity and activation of the pro-apoptotic transcription factor FOXO1 , and decreased proliferating cell nuclear antigen positive fibroblasts ( p < 0.05 )
Kayal et al., J Bone Miner Res 2010
(Diabetes Mellitus, Experimental...) :
Silencing FOXO1 using siRNA in vitro significantly reduced TNF induced apoptosis and caspase activity in differentiated chondrocytes