Gene interactions and pathways from curated databases and text-mining

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IL6 — SFTPC

Text-mined interactions from Literome

Suhr et al., Arch Dermatol Res 2003 : SPC also markedly induced IL-6 production in cultured human dermal fibroblasts in a dose- and time dependent manner
Kwon et al., J Dermatol Sci 2007 (MAP Kinase Signaling System) : We performed immunohistochemical analysis to demonstrate the IL-6 induction by SPC ... SPC markedly induced interleukin-6 (IL-6) expression in rabbit ear wound ... SPC also induced IL-6 expression at both the mRNA and protein levels in human dermal fibroblasts cultured in vitro ... Pretreatment with PD 98059, a specific MAPK kinase 1/2 inhibitor, markedly suppressed SPC induced IL-6 expression in a dose dependent manner ... Protein kinase C ( PKC ) activation by phorbol myristate acetate ( PMA ) potentiated IL-6 mRNA expression, whereas PKC inhibition by bisindolylmaleimide blocked SPC induced p42/44 ERK phosphorylation and IL-6 expression ... These results suggest that SPC induced IL-6 production is mediated by PKC dependent p42/44 ERK activation in human dermal fibroblasts cultured in vitro
Soramoto et al., Nihon Hinyokika Gakkai Zasshi 1994 (Autoimmune Diseases...) : A significant stimulation of in vitro lymphocyte proliferative response, as well as of interleukin (IL) 5 and IL-6 production by sensitized SPC were detectable when TC of mice 3-w.o. or more than were employed as stimulant
Soramoto et al., Clin Immunol Immunopathol 1993 (Autoimmune Diseases...) : A significant stimulation of interleukin 5 (IL-5) and interleukin 6 (IL-6) production by sensitized SPC was detectable when the TC from 3-week or older mice were employed as a stimulant