Gene interactions and pathways from curated databases and text-mining

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FOS — PENK

Text-mined interactions from Literome

Comb et al., NIDA Res Monogr 1992 : In the studies described herein, we demonstrate that AP-1 complexes consisting of different Jun proteins differentially regulate proenkephalin transcription at the CRE-2 element
Konradi et al., J Neurochem 1995 (Second Messenger Systems) : Despite some prior predictions, we do not find a role for c-Fos in cyclic AMP regulation of proenkephalin gene expression in neurons
Ziółkowska et al., Brain Res Mol Brain Res 1995 : Fos is not involved in the regulation of the proenkephalin gene by haloperidol in the mouse striatum ... These results suggest that Fos is not necessary for activation of the PENK gene expression, produced by chronic haloperidol application, in the striatum
Ziółkowska et al., Brain Res Mol Brain Res 1998 (Seizures) : The obtained results support the view that Fos may be involved in regulation of the PENK and PDYN gene expression in the dentate gyrus during seizures, which further suggests that the mechanisms triggering the up-regulation of both these genes in the dentate gyrus may differ from these working in other brain regions, such as the striatum and hypothalamus