Lee et al., Oncogene 2003
(Colonic Neoplasms) :
These results demonstrate that IL-4 enhances PSA expression through activation of the AR and Akt signaling pathways in LNCaP prostate cancer cells
Mazmanian et al., Nature 2008
(Colitis...) :
Purified PSA administered to animals is required to suppress pro-inflammatory interleukin-17 production by intestinal immune cells and also inhibits in vitro reactions in cell cultures
Du et al., Int Immunopharmacol 2012
:
APS also could induce CD4 ( + ) T cells to produce IL-4 , IL-2 and IFN-? and enhance IFN-? expression of CD8 ( + ) T cells